According to a recent US study, women using painkillers like aspirin available over-the-counter-OTC may not suffer an increased risk of miscarriage.
Earlier studies hinted at increase in risk of miscarriage in women who used non-steroidal anti-inflammatory drugs- NSAIDs at the time of conceiving or early pregnancy. But this has not been proven. In this study, researchers looked for possible link between miscarriage and ingestion of NSAIDs including painkillers like ibuprofen, aspirin or naproxen.
The team leader of the study, Digna Velez Edwards from Vanderbilt University, Nashville stated that the study did not show any link between increase in risk of miscarriage and usage of over-the-counter (OTC) NSAIDs in early stages of pregnancy.
Edwards said that much of the evidence suggesting the risk of miscarriage is associated with prescribed NSAIDs while most women use OTC NSAIDs occasionally for pain or aches. The team observed almost 3,000 women in the study.
Of all, 43 percent confirmed ingestion of painkillers around the time of conceiving or during early stages of pregnancy. Researchers found that almost 13 percent women suffered miscarriage during the course of the study.
The risk in these women was no greater than those who had used NSAIDs irrespective of the number of days they took the drug. But Edward suggested that it is still unclear if usage of NSAIDs or other medications during pregnancy is safe. He further indicated that ingestion of NSAIDs could pose to be a biological risk.
It is felt that the drug affects ‘prostaglandins’ which are hormone like substances which could interfere with prostaglandin changes which occur in women during early stages of pregnancy.
In general, it is found that it is best to limit ingestion of medications during pregnancy.
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